Current epidemiology and antenatal presentation of posterior urethral valves: Outcome of BAPS CASS National Audit
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In brief
In brief
National audit examining current epidemiology and presentation patterns of posterior urethral valves in the UK and Ireland, comparing contemporary data to historical 1980s cohorts. Study analyzes timing of diagnosis (antenatal vs postnatal vs late presentation) and incidence rates in boys with this leading cause of childhood bladder obstruction and renal failure.
Written by the GCMD Library team from the article.
Aim
Posterior urethral valves (PUVs) are the most common cause of congenital bladder outlet obstruction (BOO) in boys and end-stage renal failure (ESRF) in childhood. In the 1980s, 1 in 4000 boys had PUV. Presentation was 1/3 antenatal/neonatally, 1/3 postnatal, 1/3 late (>1 year). This study aimed to describe the current proportions in a contemporary cohort.
Methods
A national audit (BAPS CASS) of referrals in the UK and Ireland of boys diagnosed with suspected or confirmed PUV in a year was conducted. National registration data provided the male birth-rate. Data were presented as number (%), analysed by Mann–Whitney U-test and Chi-square test, with P