From
Dr. Alberto Tozzi
Central nervous system immunological complications of immunotherapy in pediatrics.
pubmed.ncbi.nlm.nih.gov shows its articles on its own site.
Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Oct 2026 · 1 min read
In brief
In brief
This review examines central nervous system immune-related adverse events in pediatric patients receiving immunotherapies including CAR T-cells and checkpoint inhibitors. The article synthesizes current evidence on CNS complications that are increasingly recognized but remain incompletely characterized in children.
Written by the GCMD Library team from the article.
Immunotherapies such as CAR T-cell therapy and immune checkpoint inhibitors (ICIs) have transformed pediatric cancer treatment but are increasingly associated with severe central nervous system (CNS) immune-related adverse events (irAEs), which remain poorly understood in children. This review summarizes current knowledge on CNS irAEs in children receiving CAR T-cells, ICIs, and monoclonal antibod…
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