Assessment of neurogenic bowel symptoms with the bowel dysfunction score in children with spina bifida: a prospective case–control study
link.springer.com shows its articles on its own site.
Read the article on link.springer.com ↗Article · May 2020 · 1 min read
In brief
In brief
Prospective study of 98 children demonstrates that spina bifida patients experience significantly worse bowel-related quality of life compared to healthy controls, despite active management with rectal irrigations or laxatives. Unexpectedly, no difference in quality of life was found between different bowel management strategies, suggesting need for longitudinal evaluation of treatment effectiveness.
Written by the GCMD Library team from the article.
Abstract
Aim
To compare the quality of life (QoL) in children with spina bifida with a control group of their peers using a validated questionnaire, the Neurogenic Bowel Dysfunction Score (NBDS).
Methods
The NBDS questionnaire was prospectively distributed to children attending a multi-disciplinary Spina Bifida clinic and healthy controls attending pediatric urology clinics. A score (out of 41) was assigned to each child based on their responses to the validated questionnaire. A lower score indicates better bowel function-related quality of life. SPSS software (v.25) was used for all statistical analysis.
Results
There were 98 respondents to the questionnaire, 48 children with spina bifida and 50 controls. The average age of respondents was 7.88 years (3–16 years). Of those with Spina Bifida, 33 (69%) were on retrograde rectal irrigations, [19 (58%) Peristeen® system, 11 (33%) tube rectal irrigations, and 3 (9%) Willis system], 6 (12%) were on laxatives, and 9 (19%) were on no treatment. The median NBDS for Spina Bifida patients was significantly higher 13.5 (2–32) compared to the control group 2 (0–26, p < 0.001). Amongst Spina Bifida patients, there was no difference in quality of life between the modalities of bowel management (p = 0.203).
Conclusions
Despite active bowel management, children with spina bifida report a worse quality of life compared to the control group. In those with spina bifida, the lack of a difference between various bowel management strategies, including no treatment, indicates the need for a longitudinal study to evaluate the basis for this unexpected finding.