Achieving urinary continence in cloacal exstrophy: The surgical cost
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In brief
In brief
Retrospective study of 59 cloacal exstrophy patients demonstrates that 71% achieved urinary continence through surgical intervention, requiring a median of 4 total urologic procedures including 2 continence-specific operations. Median time to continence was 11 years, with half of candidates achieving dryness by age 11.
Written by the GCMD Library team from the article.
Introduction
Cloacal exstrophy (CE) is a severe midline congenital abnormality that requires numerous surgical corrections to achieve an acceptable quality of life. Candidates for urinary continence undergo multiple procedures, most often continent bladder diversions, to become socially dry. Here, the authors investigate the number of genitourinary interventions that patients with CE undergo to attain urinary continence.
Materials and methods
A retrospective review of a prospectively maintained database of 1311 exstrophy epispadias complex patients was performed. Patients with CE who have had at least one continence procedure were included. A continence procedure was defined as bladder neck reconstruction with or without augmentation, bladder neck transection with continent urinary diversion, augmentation cystoplasty, or use of injectable bulking agents. Continence was defined as a dry interval greater than 3 hours without leakage at night.
Results
In total, 140 CE and CE variant patients have been managed at the authors' institution. Of the 116 CE patients, 59 received at least one continence procedure, 14 were excluded for incontinent diversion or cystectomy, and the remaining 43 patients are awaiting a continence procedure. At the time of analysis, 42 (71%) patients who underwent a continence procedure were dry. The median number of total urologic procedures to reach urinary continence was 4 (range 2–10). This included 1 bladder closure (range 1–3), 2 urinary continence procedures (range 1–4), and 1 (range 0–4) "other" genitourinary procedures. The median time to urinary continence was 11.0 years (95% CI [9.2–14.2]).
Conclusions
A majority of CE patients who undergo a diversion procedure can achieve urinary continence. However multiple continence procedures are likely necessary. Of patients who are candidates for a continence procedure, half will be continent by the age of 11.
Level of Evidence
Level IV, Case series with no comparison group.