A Standardized Guideline for Antibiotic Prophylaxis in Surgical Neonates
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In brief
In brief
This article addresses the gap in standardized antibiotic prophylaxis guidelines for surgical neonates, a population with limited evidence-based protocols compared to adults. It examines how recent antibiotic stewardship initiatives have driven guideline development while maintaining low surgical site infection rates, despite sparse randomized controlled trial data in this vulnerable population.
Written by the GCMD Library team from the article.
Publication date: Available online 23 January 2019
Source: Seminars in Pediatric Surgery
Author(s): Carrie Laituri, Meghan A. Arnold
Abstract
Infection following surgical procedures leads to increased morbidity and mortality in all populations. Guidelines to aid providers in the proper use of prophylactic antibiotics exist for adults, but are rare in the neonatal surgical population. A recent emphasis on appropriate antibiotic stewardship had led to the development of more guidelines without a coincident increase in surgical site infection. Robust data from randomized, controlled trials, however, remain sparse.