A single institution’s experience with the management of peripheral bronchial atresia
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In brief
In brief
Retrospective review of 28 patients with peripheral bronchial atresia shows expectant management is safe for most cases, with only 2/22 patients requiring surgery for recurrent infections. Symptom changes may indicate alternate pathology like congenital lobar overinflation, warranting surgical evaluation.
Written by the GCMD Library team from the article.
Abstract
Purpose
Peripheral bronchial atresia is a pulmonary abnormality diagnosed on postnatal computed tomography after prenatal imaging reveals a congenital lung lesion. Debate regarding management of this abnormality prompted us to review our institution’s practice patterns and outcomes.
Methods
All patients diagnosed with bronchial atresia were assessed from 6/2014 to 7/2020. Pediatric radiologists were surveyed to delineate computed tomography criteria used to diagnose peripheral bronchial atresia. Criteria were applied in an independent blinded review of postnatal imaging. Data for patients determined to have peripheral bronchial atresia and at least an initial pediatric surgical evaluation were analyzed.
Results
Twenty-eight patients with bronchial atresia received at least an initial pediatric surgical evaluation. Expectant management was planned for 22/28 (79%) patients. Two patients transitioned from an expectant management strategy to an operative strategy for recurrent respiratory infections; final pathology revealed bronchial atresia in both. Six patients were initially managed operatively; final pathology revealed bronchial atresia (n = 3) or congenital lobar overinflation (n = 3).
Conclusions
Peripheral bronchial atresia can be safely managed expectantly. A change in symptoms is suspicious for alternate lung pathology, warranting further workup and consideration for resection.
Level of evidence
Level IV.