A retrospective multicenter study of the natural history of fetal ovarian cysts
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In brief
In brief
Multicenter retrospective study examining natural history of fetal ovarian cysts found that cysts >40mm are significantly less likely to resolve spontaneously (44% vs 90% for smaller cysts), but torsion risk showed no significant size correlation. Median resolution time was 10 weeks with conservative management, suggesting size alone may not dictate intervention.
Written by the GCMD Library team from the article.
Aim
We investigated the natural history of fetal ovarian cysts to estimate the risk of torsion according to size.
Methods
Cases were identified from 1/1/2000 until 1/1/2015. Data were collected pre- and postnatally on cyst size and sonographic features until an outcome of surgery, torsion, or resolution. Fisher's exact test for categorical data and logistic regression for continuous data were used to test the significance of size on torsion; P value 50mm; however, the overall trend failed to reach statistical significance (P=0.1). Cysts of 0–40mm had a significantly higher rate of spontaneous resolution (90% vs. 44% in >40mm, P=0.003), but the rate of torsion was not significantly different (10% in 0–40mm vs. 25% in >40mm, P=0.26). The median time to postnatal resolution was 10 (5–27) weeks in those treated conservatively.
Conclusion
Cysts >40mm are significantly less likely to resolve spontaneously; however torsion showed no significant correlation with cyst size. No complications were observed in cysts