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A Pilot Study for Biliary Atresia Diagnosis: Fluorescent Imaging of Indocyanine Green in Stool
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Read the article on jpedsurg.org ↗Article · Mar 2024 · 1 min read
In brief
In brief
This pilot study explores a novel non-invasive diagnostic approach for biliary atresia using fluorescent detection of indocyanine green in infant stool samples. The method leverages ICG's exclusive biliary excretion pathway to confirm bile duct patency, potentially offering an alternative to conventional invasive cholangiography for diagnosing obstructive jaundice in neonates.
Written by the GCMD Library team from the article.
Biliary atresia is the most common cause of obstructive jaundice in infants and conventional cholangiography is the current diagnostic gold standard. Fluorescent cholangiography with indocyanine green can enhance biliary tree visualization during surgery because it is exclusively excreted into the bile ducts and eventually into the intestine. Therefore, we hypothesized that indocyanine green presence in stool could confirm bile duct patency in infants.
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