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A Novel dynamic in-vitro Model of Esophageal Button Battery Ingestion Demonstrating Benefits of Honey, but not Acetic Acid
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Read the article on sciencedirect.com ↗Article · Feb 2026 · 1 min read
In brief
In brief
This study presents a novel in-vitro model simulating esophageal button battery ingestion in children, evaluating potential pre-hospital interventions. Results demonstrate that honey shows protective benefits against battery-induced tissue damage, while acetic acid does not provide therapeutic advantage in this experimental setting.
- - Honey shows protective benefits in esophageal button battery injury models, supporting its use as a pre-hospital intervention. - Acetic acid does not demonstrate protective effects in this dynamic in-vitro esophageal button battery ingestion model. - Dynamic in-vitro models can effectively simulate esophageal button battery injuries for testing potential interventions. - Pre-hospital management strategies for button battery ingestion may benefit from honey administration based on experimental evidence.
Written by the GCMD Library team from the article.
Publication date: Available online 11 February 2026
Source: Seminars in Pediatric Surgery
Author(s): Charlotte Reich, Yannick Schmidt, Karina Khakim, Andreas Lindner, Nomin Krespach, Oliver Muensterer, Danielle S Wendling-Keim
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