A comparison of the success rate of pneumatic reduction in intussusception between general anesthesia and deep sedation: a randomized controlled trial
link.springer.com shows its articles on its own site.
Read the article on link.springer.com ↗Article · Apr 2023 · 1 min read
In brief
In brief
This randomized controlled trial compared general anesthesia versus deep sedation for pneumatic reduction of intussusception in children, finding equivalent 88% success rates. High-risk cases may benefit from general anesthesia to facilitate immediate surgical conversion if reduction fails.
Written by the GCMD Library team from the article.
Abstract
Purpose
This study was aimed to compare the success rate between patients who underwent general anesthesia and deep sedation.
Methods
Patients who were diagnosed with intussusception and had no contraindications would receive non-operative treatment first by undergoing pneumatic reduction. The patients were then split in to two groups: one group underwent general anesthesia (GA group), while the other underwent deep sedation (SD group). This study was a randomized controlled trial which compared success rate between two groups.
Results
A total of 49 episodes diagnosed with intussusception were random into 25 episodes in GA group and 24 episodes in SD group. There was no significant difference in baseline characteristic between the two groups. The success rates of GA group and SD group were equally 88.0% (p = 1.00). Sub-analysis of the success rate was lower in the patients with high-risk score for failed reduction. (Chiang Mai University Intussusception (CMUI) failed score in success VS failed = 6.9 ± 3.2 vs. 10.3 ± 3.0 p = 0.017).
Conclusion
General anesthesia and deep sedation offered similar success rates. In cases of high risk of failure, general anesthesia should be considered to accommodate the switch to surgical management in the same setting if the non-operative approach fails. The appropriate treatment and sedative protocol also increase the success of reduction.