Pulmonary vasculature development in congenital diaphragmatic hernia: a novel automated quantitative imaging analysis

This study uses AI-powered microCT imaging to quantify pulmonary vascular abnormalities in a rat model of congenital diaphragmatic hernia. Findings reveal that CDH significantly reduces small vessel numbers and disrupts the normal fractal branching pattern of pulmonary arteries, providing quantitative insights into the vascular pathology underlying pulmonary hypertension in CDH.