Evaluation of the protective and therapeutic effects of extra virgin olive oil rich in phenol in experimental model of neonatal necrotizing enterocolitis by clinical disease score, ınflammation, apoptosis, and oxidative stress markers

This experimental study demonstrates that phenol-rich extra virgin olive oil significantly reduces intestinal damage in a neonatal rat model of necrotizing enterocolitis by suppressing inflammation, oxidative stress, and apoptosis. Treatment improved clinical outcomes, reduced inflammatory markers (IL-1β, IL-6), and decreased tissue damage scores compared to untreated NEC rats.