Exosomal long non-coding RNA MALAT1: a candidate of liquid biopsy in monitoring of Wilms’ tumor

This study identifies exosomal long non-coding RNA MALAT1 as a potential non-invasive biomarker for monitoring Wilms' tumor in pediatric patients. Researchers detected MALAT1 in exosomes from tissue culture, urine, and plasma samples, finding significantly downregulated expression in WT patients compared to controls.