Early first episode of pouchitis after ileal pouch–anal anastomosis for pediatric ulcerative colitis is a risk factor for development of chronic pouchitis

Retrospective study of 52 pediatric UC patients identifies early pouchitis onset (within 15 months post-IPAA) and preoperative immunomodulator use as key predictors of chronic pouchitis development. Findings suggest enhanced surveillance protocols for high-risk patients may improve long-term pouch outcomes.