Effectiveness of Rex shunt for improving the abnormal portal hemodynamics and portal venous pathology in EHPVO animal model

This preclinical study validates a rabbit model of Rex shunt surgery for extrahepatic portal venous obstruction (EHPVO) and demonstrates that restoring portal blood flow normalizes portal pressure, reduces splenomegaly, and reverses pathological intimal hyperplasia in portal vessels. The findings support Rex shunt as an effective intervention for improving portal hemodynamics in EHPVO.