Association of PFKM gene polymorphisms and susceptibility to cryptorchidism in a Chinese Han population

Case-control study of 140 cryptorchidism patients and 227 controls identifies association between PFKM gene polymorphism rs2228500 and cryptorchidism risk in Chinese Han population. G allele and G/G genotype show significantly higher frequency in affected patients, suggesting genetic susceptibility marker for this common congenital anomaly in newborn boys.