Outcomes of Children with Well-Differentiated Fetal Hepatoblastoma Treated with Surgery Only: Report from Children's Oncology Group Trial, AHEP0731

This COG trial demonstrates that children with well-differentiated fetal hepatoblastoma completely resected at diagnosis can achieve excellent outcomes with surgery alone, without adjuvant chemotherapy. The study builds on prior evidence showing 100% pure fetal histology tumors have superior prognosis, supporting treatment de-escalation in this low-risk subset of pediatric liver malignancies.