Sildenafil Attenuates Intestinal Injury in Necrotizing Enterocolitis Independently of Endothelial Nitric Oxide Synthase

This study investigates sildenafil's protective effects against intestinal injury in necrotizing enterocolitis (NEC), a life-threatening condition affecting preterm neonates. The research demonstrates that sildenafil attenuates NEC-related intestinal damage through mechanisms independent of endothelial nitric oxide synthase, offering potential therapeutic insights for this devastating disease.