Palisading-like Arrangement of Immature Ganglion Cell in Myenteric Ganglia is a Unique Pathological Feature of Immaturity of Ganglia

Study identifies a novel 'palisading-like pattern' of immature ganglion cells in myenteric ganglia as a diagnostic marker for immaturity of ganglia, a self-resolving Hirschsprung-allied disorder. This HE-staining feature, present at birth and resolving by median age 215 days, enables accurate diagnosis without immunostaining in neonates presenting with intestinal dysmotility.