Potential role of stem cells in disease prevention based on a murine model of experimental necrotizing enterocolitis

Research exploring stem cell-based prevention strategies for necrotizing enterocolitis (NEC), a life-threatening neonatal intestinal disease with 20-30% mortality. Studies in rat models demonstrate that multiple stem cell lines, stem cell-derived exosomes, and HB-EGF equivalently reduce NEC incidence and preserve intestinal barrier function, offering promising therapeutic approaches.