Urine sodium to urine creatinine ratio as a marker of total body sodium in infants with intestinal failure

This study validates urine sodium-to-creatinine ratio (UNa:UCr) as a superior marker of total body sodium status compared to urine sodium alone in infants with intestinal failure. A UNa:UCr >35 predicted adequate growth with 92% sensitivity and correlated better with sodium intake, offering clinicians a practical tool for nutritional management in this vulnerable population.