Modified Multivisceral Transplantation with Native Spleen Removal in Rats

Researchers developed a modified heterotopic multivisceral transplantation technique in rats that includes stomach, duodenopancreatic axis, spleen, and small bowel with native spleen removal, achieving 75% survival and successful long-term outcomes beyond one week. This refined surgical model offers improved methodology for transplant research with detailed technical modifications including optimized anastomosis times and graft positioning.