Continuous epidural chloroprocaine after abdominal surgery is associated with lower postoperative opioid exposure in NICU infants

Retrospective study of 48 NICU infants undergoing abdominal surgery found that continuous epidural chloroprocaine reduced postoperative opioid consumption by 84% and shortened time to extubation by 59% compared to systemic analgesia, while maintaining adequate pain control and hemodynamic stability.