C-reactive protein/albumin ratio is a prognostic indicator for predicting surgical intervention and mortality in neonates with necrotizing enterocolitis

Retrospective study of 191 neonates demonstrates that a CRP/albumin ratio ≥3 on day 2 of NEC diagnosis significantly predicts need for surgical intervention and mortality risk in non-perforated necrotizing enterocolitis cases. This biomarker could serve as an objective criterion for clinical decision-making and parental counseling.