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Cell death induction (extrinsic versus intrinsic apoptotic pathway) by intestinal ischemia–reperfusion injury in rats is time-depended

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Topic overview

Experimental study in rats demonstrating that intestinal ischemia-reperfusion injury triggers different apoptotic mechanisms depending on reperfusion duration. Early injury (24h) activates intrinsic mitochondrial pathway via Bax/Bcl-2, while delayed injury (48h) shifts to extrinsic death receptor pathway via TNF-α and Fas-FasL signaling.

Keywords

Intestinal Ischemia-reperfusion Apoptotic Pathways Mesenteric Ischemia Cell Death Mechanisms Acute Mesenteric Ischemia Fas-fasl Pathway Mitochondrial Apoptosis

Hashtags

#IschemiaReperfusion #MesentericIschemia #ApoptosisResearch #IntestinalInjury

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How to cite: GlobalCastMD. Cell death induction (extrinsic versus intrinsic apoptotic pathway) by intestinal ischemia–reperfusion injury in rats is time-depended. GlobalCastMD Medical Library. 2021-02-10. https://library.globalcastmd.com/article/3657

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