Management of Gastroschisis: Results From the NETS2G Study, a Joint British, Irish, and Canadian Prospective Cohort Study of 1268 Infants

Large prospective cohort study (n=1268) comparing primary closure versus silo reduction in gastroschisis management across UK, Ireland, and Canada. Findings show silo reduction reduces GI complications in uncomplicated cases but increases infection risk and hospital stay, while treatment choice should be guided by presence of intestinal perforation, matting, or necrosis.