Barium enema findings in total colonic aganglionosis: a single-center, retrospective study

Retrospective study of 44 pediatric patients identifies ileocecal valve reflux as the most reliable barium enema sign for diagnosing total colonic aganglionosis, with diagnostic accuracy improving to 72-75% when combined with question-mark-shaped colon appearance. Findings support preoperative radiographic assessment to guide surgical planning in this severe form of Hirschsprung disease.