Clinical characteristics and validation of diagnosis in individuals with Hirschsprung disease and Inflammatory Bowel Disease.

Population-based cohort study validated 18 cases with both Hirschsprung disease and IBD, finding median IBD onset at age 21 with distribution similar to non-Hirschsprung IBD patients (56% Crohn's, 33% ulcerative colitis). Clinical course paralleled typical IBD with 28% requiring surgical intervention.