Prognostic profiling of children with serious post-operative complications: A novel probability model for failure to rescue

This NSQIP-Pediatric study of 45,504 cases develops a prognostic index to identify children at high risk for failure to rescue (death after major postoperative complication). Children with >6 preoperative comorbidities accounted for 80% of FTR events, with mortality rates ranging from 0.1% (low-risk) to 22.6% (high-risk), enabling targeted monitoring strategies.