Mortality trends in neonatal ECMO for pulmonary hypoplasia: A review of the Extracorporeal Life Support Organization database from 1981 to 2016

Retrospective analysis of 1,385 neonates with pulmonary hypoplasia treated with ECMO over 35 years shows 33% survival to discharge, with mortality decreasing overall but increasing for renal dysplasia cases. CDH patients had significantly higher mortality than those with renal-associated PH, likely reflecting evolving patient selection criteria as non-ECMO ventilatory support improved.