Does the Presence of a Hernia Sac Improve Survival in Newborns with Congenital Diaphragmatic Hernia? A United Kingdom Single-Center Experience

This UK single-center study of 192 CDH newborns found no statistically significant survival advantage for patients with a hernia sac (95% vs 86%, p=0.2), contrasting with smaller studies suggesting improved prognosis. The high survival rate in non-sac cases at this specialist center likely explains the lack of significance despite the larger cohort size.