Ceftriaxone Combined With Metronidazole is Superior to Cefoxitin Alone in the Management of Uncomplicated Appendicitis in Children: Results from a Multicenter Collaborative Comparative Effectiveness Study.
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Multicenter study of 846 pediatric appendicitis patients demonstrates ceftriaxone-metronidazole combination reduces surgical site infections by 90% compared to cefoxitin monotherapy (0.2% vs 2.7%). Findings support narrow-spectrum dual therapy as superior prophylaxis for uncomplicated appendicitis in children.
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How to cite: GlobalCastMD. Ceftriaxone Combined With Metronidazole is Superior to Cefoxitin Alone in the Management of Uncomplicated Appendicitis in Children: Results from a Multicenter Collaborative Comparative Effectiveness Study.. GlobalCastMD Medical Library. 2020-05-05. https://library.globalcastmd.com/article/2541
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