A prospective, double-blind, randomized, placebo-controlled trial comparing the efficacy of polyethylene glycol versus polyethylene glycol combined with topical diltiazem for treating anal fissure in children
Topic overview
Randomized controlled trial of 48 children with anal fissure found that polyethylene glycol (PEG) alone achieved similar symptom resolution compared to PEG combined with topical diltiazem at 12 weeks. Results suggest adding diltiazem provides no additional benefit over PEG monotherapy for pediatric anal fissure management.
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How to cite: GlobalCastMD. A prospective, double-blind, randomized, placebo-controlled trial comparing the efficacy of polyethylene glycol versus polyethylene glycol combined with topical diltiazem for treating anal fissure in children. GlobalCastMD Medical Library. 2020-02-10. https://library.globalcastmd.com/article/2159
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