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Interplay between collagenase and undescended testes in Adamts16 knockout rats

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Adamts16 knockout rats develop cryptorchidism due to impaired gubernacular migration during postnatal testicular descent. Histological analysis reveals excessive collagen accumulation in the inguinoscrotal fat pad when Adamts16 proteinase is absent, demonstrating that this enzyme is essential for ECM remodeling during normal testicular descent.

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How to cite: GlobalCastMD. Interplay between collagenase and undescended testes in Adamts16 knockout rats. GlobalCastMD Medical Library. 2020-02-06. https://library.globalcastmd.com/article/2152

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