Pediatric trauma venous thromboembolism prediction algorithm outperforms current anticoagulation prophylaxis guidelines: a pilot study

Retrospective study of 8,271 pediatric trauma patients validates a VTE prediction algorithm that outperforms current age-based prophylaxis guidelines, achieving 0.93 AUROC while requiring anticoagulation in significantly fewer patients (373 vs 1,935). The algorithm stratifies risk using clinical variables and demonstrates superior sensitivity and specificity compared to blanket treatment of all patients over 15 years.