Autologous Transplantation of Skin-Derived Precursor Cells in a Porcine Model

Preclinical study demonstrating autologous skin-derived precursor cells (SKPs) can be transplanted into aganglionic porcine colon, where they migrate to enteric plexuses and express neuroglial differentiation markers. Findings support potential cell-based therapy development for Hirschsprung disease and other enteric nervous system disorders.