Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids

In brief

This research demonstrates how BMP signaling coordinates mesoderm-endoderm co-differentiation to generate vascularized lung and intestinal organoids with organ-specific endothelial and mesenchymal characteristics. The multilineage organoids recapitulate human fetal organ composition and can model developmental abnormalities.

Written by the GCMD Library team from the article.