Liver Organoids Generated from Mice with Necrotizing Enterocolitis Have Reduced Regenerative Capacity
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Liver organoids derived from mice with necrotizing enterocolitis demonstrate impaired regenerative capacity, with reduced progenitor cell markers (LGR5, SOX9) and proliferation markers (Ki67, PCNA) compared to controls. This novel model reveals hepatic damage mechanisms in NEC and identifies liver progenitor cells as therapeutic targets for preventing organ injury in affected neonates.
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How to cite: GlobalCastMD. Liver Organoids Generated from Mice with Necrotizing Enterocolitis Have Reduced Regenerative Capacity. GlobalCastMD Medical Library. 2019-07-31. https://library.globalcastmd.com/article/1559
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