Impact of Capnoperitoneum on Renal Perfusion and Urine Production in Infant and Adolescent Pigs: Crystalloid versus Colloid Fluid Resuscitation

This porcine study demonstrates that CO2 pneumoperitoneum during laparoscopy significantly impairs renal perfusion and urine production in infants compared to adolescents. Colloid fluid resuscitation effectively maintained renal function during moderate-pressure capnoperitoneum, while crystalloid therapy failed to prevent persistent oliguria in infant subjects.