New article you should know by Cecilia Gigena
"Image-guided core-needle or surgical biopsy for neuroblastoma diagnosis in children: A systematic review and meta-analysis from the International Society of Pediatric Surgical Oncology (IPSO)"
Authors: Luca Pio, Hervé J Brisse, Rita Alaggio, Elisa Zambaiti, Jacob Stenman, Stefano Giuliani, Valentina Montano, Alexander Siles Hinojosa, Anders Toel Hoel, Andrea Pevere, Ahmed Abu-Zaid, Stephanie Franchi-Abella, Abdelhafeez H Abdelhafeez, Andrew M Davidoff, Paul D Losty
Full article: https://gcmd.co/42kahvV
Abstract
Background
Image-guided core-needle biopsy (IGCNB) is a widely used and valuable clinical tool for tissue diagnosis of pediatric neuroblastoma. However, open surgical biopsy remains common practice even if children undergo more invasive and painful procedures. This review aims to determine the diagnostic accuracy and safety of IGCNBs in pediatric patients with neuroblastoma.
Methods
We conducted a systematic review of peer-reviewed original articles published between 1980 and 2023, by searching "pediatric oncology," "biopsy," "interventional radiology," and "neuroblastoma." Exclusion criteria were patients older than 18 years, studies concerning non-neurogenic tumors, case reports, and language other than English. Both the systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.
Results
A total of 533 abstracts articles were analyzed. Of these, eight retrospective studies met inclusion criteria (490 infants, 270 surgical biopsies [SB], 220 image-guided biopsies). Tissue adequacy for primary diagnosis (SB: n = 265, 98%; IGCNB: n = 199, 90%; p = .1) and biological characterization (SB: n = 186, 95%; IGCNB: n = 109, 89%; p = .15) was similar with both biopsy techniques, while intraoperative transfusion rate (SB: n = 51, 22%; IGCNB: n = 12, 6%; p = .0002) and complications (%) (SB: n = 58, 21%; IGCNB: n = 14, 6%; p = .005) were higher with surgical biopsy. Length of stay was similar in both groups; however, no additional data about concurrent diagnostic or treatment procedures were available in the analyzed studies.
Conclusions
IGCNB is a safe and effective strategic approach for diagnostic workup of NB and should be considered in preferance to SB wherever possible.
Type: video · 0 min · posted 2024-02-14 Canonical: https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988 ## Chapters - [0:00](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=0) IPSO Meta-Analysis: Image-Guided vs Surgical Biopsy for Neuroblastoma ## Statements - "The systematic review and meta-analysis was conducted by IPSO" — Cecilia Gigena (clinical) [0:09](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=9) - "The review analyzed the accuracy and safety of image-guided core needle biopsy for neuroblastoma" — Cecilia Gigena (clinical) [0:09](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=9) - "The review included 8 retrospective studies with 490 patients" — Cecilia Gigena (epidemiological) [0:23](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=23) - "Tissue adequacy was not significantly different between image-guided core needle biopsy and surgical biopsy groups" — Cecilia Gigena (clinical) [0:23](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=23) - "Biological characterization of the biopsy was not significantly different between image-guided core needle biopsy and surgical biopsy groups" — Cecilia Gigena (clinical) [0:23](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=23) - "Intraoperative transfusions were higher in the surgical biopsy group compared to image-guided core needle biopsy" — Cecilia Gigena (clinical) [0:23](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=23) - "Complications were higher in the surgical biopsy group compared to image-guided core needle biopsy" — Cecilia Gigena (clinical) [0:23](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=23) - "Image-guided core needle biopsy is safe and effective for diagnosing neuroblastoma" — Cecilia Gigena (opinion) [0:43](https://library.globalcastmd.com/watch/image-guided-core-needle-or-surgical-biopsy-for-neuroblastoma-diagnosis-in-children-7988?t=43) ## Transcript You use open and percutaneous biopsy for neuroblastoma. Hi, I'm Cecilia Jina from Cincinnati Children's Hospital, and I think this is an article that you should know about. This is a systematic review and meta-analysis done by IPSO, and I wanted to analyze the accuracy and safety of image-guided core needle biopsy for neuroblastoma. And what did they find? They gathered 8 retrospective studies with 490 patients, and what they found is that tissue adequacy and biological characterization of the biopsy was not significantly different in both groups, but intraoperative transfusions and complications were higher in the surgical group. So it seems that image-guided core needle biopsy is safe and effective for diagnosed neuroblastoma. Let us know what you think and stay tuned for more articles that you should know about. --- Not medical advice · citation policy: https://library.globalcastmd.com/ai