Paula Escobar · Endoscopic nipple-sparing mastectomy: minimally invasive breast cancer surgery
Podcast14 min·Published Jul 2026

Endoscopic nipple-sparing mastectomy: minimally invasive breast cancer surgery

With Dr. Paula Escobar · hosted by Dr. Dale Shepherd
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Breast cancer
What the experts said29 expert statements
1999 was the first nipple-sparing mastectomy reported.
ClinicalPaula Escobar
Dr. Crowe at Cleveland Clinic was one of the pioneers who developed the open/conventional nipple-sparing mastectomy technique.
ClinicalPaula Escobar
Endoscopic nipple-sparing mastectomy uses the same technique as conventional nipple-sparing mastectomy but with different tools (minimally invasive approach with less scarring).
ClinicalPaula Escobar
The incision is placed in the mid-axillary line hidden by the arm or in the submammary fold, making it completely invisible.
ClinicalPaula Escobar
The procedure involves inflating/expanding the breast with CO2, then introducing laparoscopic instruments through a single incision to remove breast tissue while preserving the envelope.
ClinicalPaula Escobar
Immediate breast reconstruction is attempted at the time of mastectomy, with plastic surgeons adjusting their technique to work through the smaller incision.
ClinicalPaula Escobar
The current endoscopic technique has approximately 5 years of history in its present form.
ClinicalPaula Escobar
Minimally invasive breast surgery started in Asian countries approximately 20 years ago using mechanical arms to lift the breast, but early attempts had complications in skin flaps and nipples due to limited technology.
ClinicalPaula Escobar
The technique developed in Europe (France, Spain, Italy) using CO2 insufflation and is now being learned in the US.
ClinicalPaula Escobar
Very few surgeons in the US currently perform endoscopic nipple-sparing mastectomy, making it difficult for patients to access.
EpidemiologicalPaula Escobar
Three hands-on simulated model courses have been held in the US to train surgeons in the technique.
ClinicalPaula Escobar
Cleveland Clinic has trained multiple surgeons in the endoscopic technique, with Dr. Escobar helping to train colleagues.
ClinicalPaula Escobar
Robotic breast surgery takes a long time, requires a robot, has a long learning curve, and is not FDA approved (currently only available in trials at limited US centers).
ClinicalPaula Escobar
Endoscopic surgery uses instruments already available for abdominal/hernia surgery, requiring no special equipment purchases.
ClinicalPaula Escobar
Operating time for endoscopic surgery, when experienced, is similar to open/conventional surgery.
ClinicalPaula Escobar
Indications for endoscopic nipple-sparing mastectomy are very similar to conventional nipple-sparing mastectomy.
ClinicalPaula Escobar
Patients are not good candidates if tumor involves the skin, is very close to the muscle, is very close to the nipple, or involves the skin.
ClinicalPaula Escobar
Best candidates have cup A, B, or C breasts (not larger breasts at current learning curve stage).
ClinicalPaula Escobar
Procedure is performed on patients with no ptosis or ptosis grade 1 or 2, as higher grades result in poor cosmetic outcomes.
ClinicalPaula Escobar
Patient advantages include superior cosmetic outcome, hidden/invisible scar, and likely quicker recovery with less pain (similar to laparoscopic vs open abdominal surgery).
ClinicalPaula Escobar
Preliminary studies suggest patients have better sensation in the nipple and mastectomy skin flap, though quality trials are needed.
ClinicalPaula Escobar
Initial patients have been very happy with the procedure and recovered very quickly.
ClinicalPaula Escobar
Oncological safety of conventional nipple-sparing mastectomy has been proven by data.
ClinicalPaula Escobar
Endoscopic technique may be better than conventional because the magnified screen visualization allows better handling of the mastectomy skin flap and improved visualization of breast tissue behind the nipple and axillary tail.
OpinionPaula Escobar
No insurance coverage problems have occurred; procedure is coded as skin-sparing mastectomy since no specific code exists yet.
ClinicalPaula Escobar
Cleveland Clinic has performed endoscopic nipple-sparing mastectomy with endoscopically-assisted sentinel node retrieval through a single incision.
ClinicalPaula Escobar
Future applications include axillary dissection and lumpectomy for tumors in inner portions of the breast (scar in axilla instead of breast).
ClinicalPaula Escobar
The technique has been used for gynecomastia surgery in one male patient.
ClinicalPaula Escobar
Dr. Escobar predicts widespread adoption will occur similar to laparoscopic cholecystectomy, driven by patient experience, outcomes, and faster recovery.
OpinionPaula Escobar