StayCurrent Espanol · Un paso mas cerca del tratamiento de problemas del neurodesarrollo en pacientes con RCIU
Video·Published Mar 2023Older

Un paso mas cerca del tratamiento de problemas del neurodesarrollo en pacientes con RCIU

hosted by Dr. Cecilia Gigena

Chapter 1 of 4

Introduction

Introduction to IUGR neurodevelopmental treatment research

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What the experts said0 expert statements · 8 host summaries
The study was a preclinical study conducted at Boston Children's Hospital together with Harvard Medical School
Host summaryCecilia Gigena summarizing a resource · not cited in answers
The study objective was to determine if mesenchymal stem cell therapy via amniotic fluid could reduce brain inflammation in patients with intrauterine growth restriction
Host summaryCecilia Gigena summarizing a resource · not cited in answers
Researchers created a rat model of intrauterine growth restriction and divided subjects into four groups
Host summaryCecilia Gigena summarizing a resource · not cited in answers
Group 1 received no treatment, Group 2 received only saline solution, Group 3 received MSC therapy via amniotic fluid, and Group 4 received MSC therapy with a primer before the mesenchymal cells
Host summaryCecilia Gigena summarizing a resource · not cited in answers
Untreated patients and those who received only saline solution had significantly lower brain weight
Host summaryCecilia Gigena summarizing a resource · not cited in answers
Patients treated with mesenchymal stem cell therapy via amniotic fluid had greater brain weight
Host summaryCecilia Gigena summarizing a resource · not cited in answers
Patients who received MSC therapy via amniotic fluid with a primer had significantly less expression of interleukin-beta and TNF-alpha in the brain
Host summaryCecilia Gigena summarizing a resource · not cited in answers
Reduced expression of interleukin-beta and TNF-alpha indicates less brain inflammation
Host summaryCecilia Gigena summarizing a resource · not cited in answers