Is posterior urethral valves hereditary?

So, um, one of the other questions that was, uh, posed to us by a family was, um, is the diagnosis or the condition of post-lethal valves hereditary, and, um, You know, it is a sporadic event that happens during embryological development, and it is very important for the family to know that there's nothing that the mom did during the pregnancy that caused this to happen to the baby. And nothing that the mom could have done to prevent this from happening. It just is one of those things that unfortunately, when you think of the miracle of human life, it's one cell from the dad, one cell from the mom coming together, we get a fertilized embryo, and 9 months later, there is a very complex multi-billion cellular organism called a human being that results from that pregnancy. And there's a very complicated 3 dimensional map where cells have to show up at the right time, at the right place in order for organs to develop properly. And the diagnosis of valves or the condition of valves simply arises because some cells were not following that very important roadmap to the T, and as a result, they were left behind and that those are the valves. Um, we do have a few families where we actually have siblings. So we have a couple of families where we have, uh, one or two brothers who have been affected, and this is a condition that only affects boys. It will never be seen in a female because the female urethra develops differently than a male urethra. And, um, we have one family here where we have a father and son, but that is a very unusual, um, condition that we, we have that, uh, family where both the father and the son were affected by the same condition which arises from a sporadic event during development. So it is not a genetic condition in that it doesn't follow the traditional inheritance patterns. Uh, there definitely is some component of genetics, uh, involvement, and there's gonna be, as we, we have a better understanding of the molecular basis of this condition and why some children, when their bladders are affected, will have a near normal bladder and why some children's bladders just become so affected and will never become normal. So, there is a different sort of genetic control over what's happening, but it's not passed on from parent to child in a traditional sense of inheritance.