From
Dr. Alexander Bondoc
Machine Perfusion and Mitigating Risk Factors for Delayed Graft Function in Pediatric Kidney Transplant Recipients.
pubmed.ncbi.nlm.nih.gov shows its articles on its own site.
Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Oct 2026 · 1 min read
In brief
In brief
This article examines machine perfusion technology as a strategy to reduce delayed graft function in pediatric kidney transplant recipients by mitigating ischemia-reperfusion injury during organ transport. Reviews evidence on how prolonged ischemia times affect graft outcomes and explores MP's potential to improve allograft survival in the pediatric population.
Written by the GCMD Library team from the article.
Kidney transplantation confers prolonged and improved quality of life versus dialysis for patients with end-stage kidney disease (ESKD). Delayed graft function (DGF) increases the risk of allograft rejection and decreases allograft survival. In adults, prolonged warm (WIT) and cold ischemia time (CIT) increase risk of DGF, and machine perfusion (MP) during organ transportation reduces this risk. H…
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