Trisomy 21 and Anorectal Malformation: What to Watch For
Carousel1 min read·Published Oct 2026

Trisomy 21 and Anorectal Malformation: What to Watch For

Title slide showing neonatal incubator illustration for case on Trisomy 21 with anorectal malformation
Warning slide explaining that absent ganglion cells in fistula tissue doesn't confirm Hirschsprung disease diagnosis.
Checklist showing three clinical indications for Hirschsprung disease workup in pediatric patients.
Title slide announcing a full breakdown video available via link in bio, sponsored by Cincinnati Children's.
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Carousel · Oct 2026 · 1 min read

In brief

In brief

Educational carousel addressing the clinical considerations and surveillance strategies for managing anorectal malformations in patients with trisomy 21. Provides guidance on associated anomalies, surgical planning, and postoperative monitoring specific to this patient population.

Written by the GCMD Library team from the carousel.

Slides

5 pages · click to turn to one

A structured comparison chart displaying three treatment modalities side-by-side with clinical outcome data. Each column contains procedure illustrations, percentage metrics in large typography, and bullet-pointed clinical findings. Color coding differentiates the three approaches, with green highlighting the highest-performing option.

Colorectal surgery. A social-media carousel made possible by Cincinnati Children's.
The text in the image

Pediatric Achalasia: Surgical Approach Comparison | Heller Myotomy | 78% Success Rate | Esophageal Dilatation | 45% Success Rate | POEM (Peroral Endoscopic Myotomy) | 99% Success Rate | Systematic Review: 742 Cases | Complications | Training Requirements | Long-term Outcomes | Clinical Considerations

The text on each slide
  1. Made possible by | Cincinnati Children's changing the outcome together | A PATIENT WITH TRISOMY 21 AND AN ANORECTAL MALFORMATION. | What should you be watching for? | Swipe right
  2. Cincinnati Children's | A DIAGNOSTIC TRAP: | "Absent ganglion cells in fistula tissue means Hirschsprung's." | NOT NECESSARILY TRUE | Fistula tissue isn't physiologic to begin with. | In one Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) single-center series: | 91% of fistula specimens had ganglion cells — absence alone doesn't confirm the diagnosis | Swipe right
  3. Cincinnati Children's | SO WHAT ACTUALLY PREDICTS IT? | ~4% had both ARM and Hirschsprung's — rare | 2 of 3 dual-diagnosis patients had Trisomy 21 | Aaron Garrison, MD | Pediatric Surgeon, | Cincinnati Children's | Swipe right
  4. Cincinnati Children's changing the outcome together | WHEN TO WORK THEM UP: | 1 | A complex anorectal patient | 2 | Not responding to laxatives or enemas | 3 | Has a chromosomal anomaly | All three? Work them up for Hirschsprung's. | Swipe right
  5. Made possible by Cincinnati Children's changing the outcome together | FULL BREAKDOWN IN OUR LATEST VIDEO, LINK IN BIO! | GC
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