Maternal Hyperglycemia and Adult Offspring Overweight and Obesity: Is Birthweight a Mediator?

Lizzy Lee from Cincinnati Children's discusses a study examining the link between maternal hyperglycemia during pregnancy and adult offspring overweight and obesity. The research found that higher and more variable maternal blood sugar, especially in the third trimester, was linked to increased adult obesity risk in offspring. Interestingly, birth weight did not fully mediate this long-term effect but had its own independent association with adult BMI, suggesting a more complex interplay of factors.