What if curing a rare pancreatic tumor sets the stage for chronic pancreatitis? I'm Lizzie Lee from Cincinnati Children's, and this is an article you should know about. Solid pseudopapillary neoplasms are uncommon, but in pediatric patients, they're one of the most frequent pancreatic tumors. Surgery is usually curative and outcomes are excellent, but this single center study tells a deeper story. 10 adolescent girls underwent surgical resection. Most recovered well, but 3 went on to develop acute recurrent or chronic pancreatitis. Here's the striking part. Every patient who developed ongoing pancreatitis had genetic risk factors like the CFTR gene variant, or they had pancreas divisum. Some ultimately required completion pancreatectomy. What's the takeaway? Even low grade tumors can carry high stakes consequences. Identifying genetic and anatomic risk factors before doing surgery may change how we manage these patients. Let us know what you think in the comments below and stay tuned for more articles that you should know about.