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Long-Term Follow-Up of Surgical Outcomes for Patients With Wilms Tumor and Neuroblastoma

Video Published 2026-02-27 Updated 2026-08-01

Timestops (3)

0:00
You just surgically treated your patient with Wilms tumor or…
You just surgically treated your patient with Wilms tumor or neuroblastoma. Now what? Hi, I'm Doctor Sophia Skerhorn fro…
0:21
Required a repeat laparotomy
Required a repeat laparotomy, most commonly for small bowel obstruction or tumor recurrence. In Wilm's tumor, obstructio…
0:43
Not increased compared to the population norms.
Not increased compared to the population norms. Finally, scoliosis occurred in roughly 10 to 13% of patients, higher tha…

Topic Overview

A single-institution cohort study following Wilms tumor and neuroblastoma survivors for a mean of 27 years after open oncologic resection. Fourteen percent required repeat laparotomy, most commonly for small bowel obstruction or tumor recurrence, with timing differing by tumor type: Wilms tumor obstructions typically occurred within the first year, while neuroblastoma obstructions often developed more than a decade later. Scoliosis occurred in 10-13% of patients, higher than the general population. The study emphasizes that surgical care extends decades beyond resection, requiring long-term follow-up for late complications.

Key Takeaways

  • 14% of Wilms/neuroblastoma survivors required repeat laparotomy, most often for bowel obstruction or recurrence. (0:20)
  • Obstruction timing differs: Wilms within 1 year vs. neuroblastoma often >10 years post-op. (0:26)
  • Scoliosis affects 10-13% of survivors—higher than general population—from surgery ± radiation. (0:45)
  • Late complications emerge decades after resection, requiring lifelong surveillance beyond routine oncology follow-up. (0:11)

Inside this episode

Kai, the Library's AI content creator, listened to this episode and mapped who's speaking, the chapters, key claims, and cases. Every item links to the exact moment in the recording.

AI-enriched

Who's speaking

  • Dr. Sophia Skerhorn — guest

Chapters

  • 0:00Long-Term Surgical Outcomes in Wilms Tumor and Neuroblastoma Survivors — Dr. Skerhorn presents a 27-year follow-up study examining late surgical complications after open oncologic resection for Wilms tumor and neuroblastoma, including rates of repeat laparotomy, scoliosis, and other long-term sequelae.

Key claims

  • 0:11This single institution cohort followed survivors for a mean of 27 years after open oncologic resection for Wilms tumor and neuroblastoma — Dr. Sophia Skerhorn
  • 0:2014% of patients required a repeat laparotomy — Dr. Sophia Skerhorn
  • 0:21The most common indications for repeat laparotomy were small bowel obstruction or tumor recurrence — Dr. Sophia Skerhorn
  • 0:26In Wilms tumor, obstruction typically occurred within the first year — Dr. Sophia Skerhorn
  • 0:29In neuroblastoma, obstruction often developed more than a decade later, well beyond routine follow-up — Dr. Sophia Skerhorn
  • 0:34Radiation dose was not associated with re-operation risk — Dr. Sophia Skerhorn
  • 0:37Secondary malignancy was uncommon in this cohort — Dr. Sophia Skerhorn
  • 0:37Hypertension after nephrectomy was not increased compared to population norms — Dr. Sophia Skerhorn
  • 0:45Scoliosis occurred in roughly 10 to 13% of patients, higher than the general population — Dr. Sophia Skerhorn
  • 0:45Scoliosis has multi-factorial contributors including surgery and possibly radiation — Dr. Sophia Skerhorn
  • 0:58Even decades after treatment, these patients remain at risk for late complications that warrant long-term counseling and follow-up — Dr. Sophia Skerhorn
This episode was analyzed and enriched by Kai, the Library's AI content creator. Every item links to the moment it comes from — click a timestamp to listen in context.

Keywords

Wilms tumor neuroblastoma small bowel obstruction tumor recurrence secondary malignancy hypertension scoliosis open oncologic resection repeat laparotomy nephrectomy radiation Cincinnati Children's

Hashtags

#WilmsTumor #Neuroblastoma #SurgicalOutcomes #LongTermFollowUp #PediatricOncology #SurgicalSequelae #Laparotomy #TumorRecurrence #Nephrectomy #SecondaryMalignancy #Hypertension #Scoliosis #RadiationDose #OncologicResection #PatientCounseling #Survivorship #LateComplications #CincinnatiChildrens #CohortStudy #SurvivorshipCare

Transcript

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