Journal of Pediatric Surgery Article Review: 2nd Quarter (Apr-Jun) 2024
With Dr. Mike Livingston & Dr. Ilana Barris & Dr. Emma Moore & Dr. Sebastian King · hosted by Dr. M. Gootee · StayCurrentMD
Cued at 8:12 · stops at 8:57 · press play
Educational content from recorded physician discussions — not medical advice. Talk to your (or your child's) care team about your situation.
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Jingying Jiang, MD - Best of the Best in Pediatric Surgery 2024
Dr. Todd Ponsky · 6 min · Published Feb 2024
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Biliary Atresia - Robert Parry: Update Course 2014
24 min · Published Nov 2018
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Biliary Atresia-Case Presentation and Panel Discussion: Update Course 2014
23 min · Published Jul 2017
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Clinical Characteristics and Prognosis of Biliary Atresia with Low Serum Matrix Metalloproteinase-7 Levels
55 s · Published Jul 2024
Podcast
Update Course Rewind: 2024 Top Ten Key Takeaways
Ramy Shaaban · 18 min · Published Jun 2025
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Prof. Shilpa Sharma - Best of the Best in Pediatric Surgery 2024
Dr. Todd Ponsky · 5 min · Published Feb 2024
Only a few other public items share this expert — go deeper there →
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Pediatric Surgical Oncology Research Collaborative (PSORC): Studying Rare Pediatric Tumors
56 s · Published May 2026
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Update Course Rewind 2025: Hirschsprung + ARM: Rare but Real
1 min · Published May 2026
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Update Course Rewind 2025: Hirschsprung + ARM: Rare but Real
1 min · Published May 2026
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Pooling Patients to Study Rare Pediatric Tumors: An Introduction to PSORC
56 s · Published May 2026
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The fetal frontier: A review of current and emerging fetal therapies for genetic diseases
44 s · Published May 2026
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Indocyanine green assists with sentinel lymph node mapping in pediatric and adolescent patients
1 min · Published May 2026
What the experts said
Patients with uncomplicated gastroschisis who had some exposure to formula in the first 28 days of life did not have increased risk of necrotizing enterocolitis or major differences in reaching full enteral feeds
Patients with uncomplicated gastroschisis who received some formula appeared to have slightly faster time getting to full feeds, likely related to timing of closure rather than feeding type
The life course progression of anorectal malformation and Hirschsprung disease is not well understood
Barriers and enablers of successful transition for surgical colorectal patients showed agreement with those for medical patients that existing guidelines were based on
Patients felt that clinicians did not always understand the need for transitioning their child's care from pediatric to adult settings, including the reasons, processes, and how to make transitions smooth
There was little evidence that transfer of colorectal patients from pediatric to adult care happened in a timely or coordinated manner
No models of transfer of care for colorectal patients from pediatric to adult settings were identified in the systematic review
MMP-7 (matrix metalloproteinase 7) are proteolytic peptidases that break down peptide bonds for amino acids and are part of tissue remodeling processes, playing roles in tissue repair, arthritis, metastasis, and cirrhosis
Higher levels of MMP-7 are associated with the diagnosis of biliary atresia
In a cohort of 329 biliary atresia cases from July 2020 to December 2022, 40 were classified as low MMP-7
Low levels of MMP-7 in biliary atresia patients are associated with low levels of preoperative GGT (gamma glutamyl transpeptidase) and direct bilirubin
GGT (gamma glutamyl transpeptidase) is an enzyme found in high levels in liver, kidney, pancreas, heart, and brain, and blood GGT levels are used to detect diseases of the liver and bile ducts
Biliary atresia has variable outcomes even within one center, with patients who anatomically look similar having dramatically different outcomes
Having lower MMP-7 levels within the cohort of biliary atresia patients is associated with worse prognosis
The mechanism of why low MMP-7 levels in biliary atresia patients leads to worse prognosis is unknown
In a Canadian cohort of 411 infants with gastroschisis treated at CAPSNET centers from 2014 to 2022, 144 were excluded due to gestational age, birth weight, other congenital anomalies, or complicated gastroschisis, leaving 267 participants
Of 267 uncomplicated gastroschisis patients, 78% received exclusive breast milk in the first 28 days of life and 22% received supplemental or exclusive formula
There were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, or length of stay in uncomplicated gastroschisis
Patients with uncomplicated gastroschisis who received exclusive breast milk in the first 28 days were far more likely to transition to exclusive breastfeeding: 73% compared to 11% in those with formula exposure
A systematic review on transition from pediatric to adult care for colorectal conditions included 8 studies with patient, parent, and clinician perspectives, focusing on patients aged 10-30 years with anorectal malformation or Hirschsprung disease
There is a group of colorectal patients discharged from care in late childhood around age 10 years, and another group that remains in pediatric care way beyond the normal age of transfer to adult care (around 25 years)