ERNICA evidence based guideline on omphalocele (2026)
Guideline1 min read·Published Nov 2026

ERNICA evidence based guideline on omphalocele (2026)

Guideline · Nov 2026 · 1 min read

In brief

In brief

ERNICA's evidence-based guideline addresses management of omphalocele, a congenital abdominal wall defect with significant morbidity and practice variation. This guideline provides standardized clinical decision-making recommendations for a condition previously lacking evidence-based guidance.

  • Omphalocele is a congenital abdominal wall defect with significant morbidity and wide variation in clinical management approaches.
  • No evidence-based guidelines existed for omphalocele management prior to this ERNICA publication.
  • This guideline provides standardized clinical decision-making framework for rare congenital anomalies across European centers.
  • ERNICA aims to reduce practice variation and improve outcomes through evidence-based consensus recommendations.

Written by the GCMD Library team from the guideline.

Omphalocele is a congenital defect of the abdominal wall with high morbidity and high practice variation. Evidence based guidance on its management is currently absent. The European Reference Network for Rare Inherited and Congenital Anomalies (ERNICA) developed this guideline to aid clinical decision-making.

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This guideline lives on pmc.ncbi.nlm.nih.gov.

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